However, the amount of time it remains effective depends on the individual. As with other opioid drugs, fentanyl binds to the receptors in the brain that affect pain and emotion. This causes feelings of well-being (euphoria) and relaxation and relieves pain. This campaign also shows the difference between counterfeit pills and real pills. As Vox’s German Lopez previously explained, fentanyl has been around since the 1960s, but its illicit use has spiked in recent years.
Naloxone: Overdose Reversal Drug
Recovery is possible with the proper support and treatment. Because the drug is less expensive than other opioids, people making it illegally commonly mix it into drugs such as heroin, cocaine, or methamphetamines. If you buy drugs illegally, there is a chance fentanyl can be in them.

Administration

Although healthcare professionals consider fentanyl safe and effective when a person uses it in a monitored medical setting, the drug carries a high potential for misuse, also known as abuse. Medications are the standard treatment for fentanyl addiction.32,33 Several medications have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of opioid use disorder. Another medication, lofexidine, has been approved for treatment of withdrawal symptoms.34 See “Medications for Opioid Use Disorder” for more information. Using fentanyl regularly can lead to an opioid use disorder (OUD).
- Now that shipments from China have come under suspicion, the sellers told the investigators that they preferred to ship through Europe.
- After you talk with your doctor, you will sign a form acknowledging that you understand the risks of using fentanyl and that you will follow your doctor’s instructions to use the medication safely.
- A person with a substance use disorder might obtain fentanyl by misusing prescribed medication or acquiring the drug from an illegal laboratory.
- According to the report, most of this fentanyl originates in China.
However, evidence has shown a high association between willingness to use a harm reduction program and subsequent uptake of the intervention among people who use drugs 38. Beginning in May 2017, we recruited participants from the 2015 RAPIDS study, 61% of whom previously agreed to be contacted for future research studies. We expanded the age and drug use eligibility criteria created based on our recent research of the fentanyl overdose epidemic in Rhode Island 19.
Pain Management
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. “People are struggling from the effects of addiction,” said Tiffany Champagne-Langabeer, senior author of a new investigation of illegal drug sales. “This study shines a light on the sophisticated methods of how the supply of opioids is coming into this country.”
- A person exhibiting the symptoms of overdose should get immediate medical attention.
- He progressed to prescription painkillers, and then, when they became too expensive, to heroin.
- Five or six times a day, a man from Texas injects a dose of carefully measured fentanyl.
- As Vox’s German Lopez previously explained, fentanyl has been around since the 1960s, but its illicit use has spiked in recent years.
Conditions & Services
According to the CDC, overdoses involving synthetic opioids increased by 72.2% from 2014 to 2015. Because fentanyl is about 50 to 100 times more potent than morphine, even a very small dose of fentanyl can be deadly. Using a drug that has been contaminated with or replaced by fentanyl can greatly increase the risk of a life-threatening overdose.
What Is Fentanyl’s Role In The Overdose And Addiction Crisis?
Its potency and widespread availability have contributed to a dramatic increase in opioid-related deaths. Specifically, at least 80% of overdoses are due to non-prescription substances. This percentage may be even higher as fentanyl can easily be mixed with other drugs, often without the user’s knowledge, which has made it particularly dangerous. Initial reports of fentanyl abuse were linked to prescription products, but in recent years, illicit fentanyl has become the most commonly abused form. In fact, most fentanyl-related deaths are from fentanyl made in illegal laboratories. Fentanyl is heavily trafficked into the US from other countries and sold as pills or powders, and it has largely replaced heroin in the drug supply.

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She called EMS, and they were brought to an emergency room. Her partner was pronounced dead, and his autopsy also showed fentanyl in his blood. The effects of fentanyl last a few hours, but it can be detected in your urine, hair and blood far longer. Fentanyl can be detected in urine tests 24 to 72 hours after last use; in blood tests up to 48 hours; and in hair up to three months after last use.

Keep track of how much fentanyl is left so you will know if any is missing. Store fentanyl at room temperature and away from excess heat and moisture (not in the bathroom). Do not stop using fentanyl without talking to your doctor.
Donate And Enjoy An Ad-free Experience
This combination can result in an individual consuming a much stronger substance than they are used to, resulting in overdose and possibly death. The DEA has found an average of 2.4 milligrams of fentanyl in the pills they test (DEA, 2024). Naloxone/naltrexone are robust opioid antagonists that function by blocking µ-receptors.
Fentanyl is not only much stronger than other opioids, but it’s often added to illicit drugs without people knowing. People making illegal fentanyl often do this because it’s less expensive to use fentanyl than other drugs. Fentanyl is a human-made opioid used to treat severe pain. The drug interacts with receptors in your brain to create feelings of pain relief, relaxation, contentment, and pleasure.
It remains one of the most commonly used opioids in controlled medical settings or advanced cancer pain. Fentanyl also can increase feelings of pleasure, often referred to as euphoria. Other effects can include drowsiness, nausea, confusion, constipation and addiction.
As part of the program, your doctor will talk with you about the risks and benefits of using fentanyl and about how to safely use, store, and dispose of the medication. After you talk with your doctor, you will sign a form acknowledging that you understand the risks of using fentanyl and that you will follow your doctor’s instructions to use the medication safely. Your doctor will give you more information about the program and how to get your medication and will answer any questions you have about the program and your treatment with fentanyl. There are two types of fentanyl – pharmaceutical fentanyl and illegally made fentanyl. If the patient has used a monoamine oxidase inhibitor in the previous 14 days, fentanyl is contraindicated.
One should always weigh the risks vs the benefits of a drug. Many may be worried about stopping prescription fentanyl due to fear of withdrawal symptoms. There is a high probability a person will have withdrawal symptoms after two weeks of use.