Figure 2 shows the signs and symptoms of an opioid overdose. If someone has experienced an overdose from an opioid, including fentanyl, call and administer naloxone. It is safe to touch the person and items that may have fentanyl on them (like a doorknob) because fentanyl cannot be absorbed through the skin with casual use (Connolly, 2022).
Prescription fentanyl is available under such names as Actiq®, Duragesic®, and Sublimaze® in the form of tablets, an injectable liquid, lozenges and patches. Overdose prevention is a CDC priority that impacts families and communities. Drug overdose is a leading cause of preventable death in the U.S.

There Are Additional Harm Reduction Techniques That Can Keep Users Safer

Food and Drug Administration (FDA) for the treatment of opioid use disorder. Another medication, lofexidine, has been approved for treatment of withdrawal symptoms.34 See “Medications for Opioid Use Disorder” for more information. Naloxone is a temporary treatment, and its effects do not last long.
In An Emergency? Need Treatment?
First responders will likely administer naloxone if you haven’t already, or give it to them again. Naloxone only works in the body for 30 to 90 minutes, so it’s possible for someone to still have overdose effects after the medication wears off or needs multiple doses. While it’s safe for your doctor to give you fentanyl in a medical setting, some people abuse it, which can lead to an overdose. Many fatal overdoses thought to be from heroin have been from fentanyl.
- The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland.
- Illegal fentanyl can be used in the same ways as prescribed fentanyl.
- The claim that some of the colors have a stronger effect than others is a myth.
- But today fentanyl can be ordered on the internet, by drug dealers and addicts, for an online overdose.
The Rise And Concern Of Counterfeit Pills

In order to find them, you would have to dial your time travel device back to the turn of the 20th century. In the early 1900s, one of the most dangerous and addicting opioids was being sold by pharmacists over the counter. Unfortunately, This led to an increase in levels of addiction. Although most often used to cut powdered opiates, fentanyl is also used to cut pills and drugs like cocaine, ketamine, methamphetamines (like ADHD pills), and benzodiazepines (like Xanax). Before taking fentanyl, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take.
Lifestyle Quizzes
Comparable to fentanyl, fentanyl analogs have similar chemical structure and effects. Common pharmaceutical industry fentanyl analogs used during surgery include sufentanil (Sufenta), alfentanil (Alfenta) and remifentanil (Ultiva). There are more than 30 nonpharmaceutical-grade fentanyl analogs circulating on the illicit drug market, many of which cannot be detected on standard urine drug screens. The use of fentanyl citrate injection with CYP3A4 inducers or stopping the CYP3A4 inhibitor will require close and repetitive monitoring of the patient.
Dosage For Severe Chronic Pain
Since fentanyl lacks an odor or taste, some drug users don’t know what they’re dealing with until it’s too late. OTC generally means that you can buy a drug without a prescription. A stated in this article, in certain states, it is possible to buy a very potent drug that binds strongly to opioid receptors without a prescription. If you want to buy this drug, you will have to speak to your pharmacist. AddictionResource.net, and its parent company Recovery Guide LLC, is not a treatment provider and does not offer medical advice or clinical services. We receive compensation from Treatment X in exchange for ad placement.
CONSULTING SERVICES
- “Fentanyl is in the supply of many drugs on the street,” explains Dr. Donald.
- Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
- Browse our directory or reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA) for more information about addiction recovery.
- Despite these programs, the internet has made buying almost anything online an option.
The medication will reverse the effects of fentanyl and block future effects. However, naloxone only stays in the body for a short time. If a person appears to experience overdose symptoms again, they may require another dose.
Illicit fentanyl use has increased sharply over the last decade and has significantly contributed to drug-related overdose and deaths. Illicit fentanyl is often mixed with other drugs like heroin, cocaine, xylazine, counterfeit prescription pills, or legitimate prescriptions. Thus, consumers may unknowingly ingest fentanyl, increasing the risk of overdose and death. Naloxone/naltrexone are robust opioid antagonists that function by blocking µ-receptors.
Chronic Pain
However, this is not a reliable indicator of whether a person is taking real fentanyl or not. Fentanyl use can result in death even with one dose, especially if a person accidentally takes it incorrectly. People who take fentanyl may develop a tolerance to high doses, meaning that more of the drug is needed to achieve the desired effect. Repeated fentanyl use can lead to dependence, which means that the person’s body gets used to the presence of the drug.

While it works quickly, naloxone is a temporary solution that works for 30 to 90 minutes. It’s available both for those who have been prescribed fentanyl and those who are misusing fentanyl. Naloxone may be available without a prescription at community-based programs, local public health groups or local health departments.
Fentanyl’s strength increases this risk of overdose substantially. Synthetic opioids sold illicitly can be mixed with heroin or cocaine, which amplifies its potency and potential danger. This is particularly dangerous if an individual who uses illegal substances like heroin or intentionally misuses prescription drugs is unaware that fentanyl could be in it. The campaign targeted areas that had seen an increase in overdoses as well as areas where people use drugs recreationally. Oregon is experiencing an influx of fentanyl in the form of counterfeit pills.